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De status van oxidatieve stress kan bepaald worden door de ratio van gereduceerd (GSH) en geoxideerd glutathion (GSSG)
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However, researchers estimate that the lethal dose of GHK-Cu would be about 330 mg/kg of body weight, which is over 300 times larger than its known effective dose
Heres the realistic timeline: Phase 3 trials (AMAZE program): - AMAZE 1 (obesity) started February 2026, enrolling ~1,150 participants - Primary completion estimated: June 2029 - Phase 3 in T2D also being planned following the ADA 2026 data US FDA approval (projected): Q4 2030 at the earliest (GlobalData estimate) EU EMA approval (projected): Q1 2031 at the earliest Bulgaria and Eastern Europe: Typically 612 months after EMA approval for market access, depending on national reimbursement negotiations
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